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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886
EISSN: 0028-3886
Vol. 58, No. 5, 2010, pp. 761-763
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Bioline Code: ni10208
Full paper language: English
Document type: Case Report
Document available free of charge
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Neurology India, Vol. 58, No. 5, 2010, pp. 761-763
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Gabapentin as a rescue drug in D-penicillamine-induced status dystonicus in patients with Wilson disease
Paliwal, Vimal K.; Gupta, Pankaj K. & Pradhan, Sunil
Abstract
D-penicillamine induced status dystonicus is a unique but serious drug related complication in a subset of patients with Wilson disease. Patho-physiological basis of its occurrence is not known. It often responds poorly to anti dystonia medications. We present three patients with Wilson disease who developed severe paroxysmal dystonic spells after receiving D-penicillamine treatment. All three patients responded well to gabapentin after failing to respond to other anti dystonia drugs.
Keywords
Status dystonicus; D-penicillamine; gabapentin; Wilson′s disease
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