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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886
EISSN: 0028-3886
Vol. 58, No. 5, 2010, pp. 778-780
Bioline Code: ni10213
Full paper language: English
Document type: Case Report
Document available free of charge

Neurology India, Vol. 58, No. 5, 2010, pp. 778-780

 en Malignant prolactinoma: A rare case report
Trivedi, Priti; Gupta, Anuja; Pasricha, Sunil & Patel, Dipak


Pituitary carcinomas are rare adenohypophyseal tumors with cerebrospinal or extracranial metastasis. None of the histologic findings distinguish pituitary adenoma from carcinoma. We describe clinico-pathological and immunohistological features of malignant prolactinoma. The patient initially presented with a prolactin-secreting pituitary adenoma. The tumor showed aggressive clinical course presenting with repeated recurrences and eventually metastasized to multiple bones. MIB-1 and p53 labeling indices were also compared in primary adenoma, recurrent invasive adenoma and metastatic tumor.

MIB-1, pituitary carcinoma, p53

© Copyright 2010 Neurology India.
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