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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886 EISSN: 0028-3886
Vol. 59, No. 1, 2011, pp. 101-103
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Bioline Code: ni11025
Full paper language: English
Document type: Report
Document available free of charge
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Neurology India, Vol. 59, No. 1, 2011, pp. 101-103
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Short-course treatment in neurobrucellosis: A study in Iran
Asadipooya, Kamyar; Dehghanian, Amirreza; Omrani, Gholam Hossein Ranjbar. & Abbasi, Farhad
Abstract
Neurobrucellosis is a rare neurological complication of brucellosis. This report describes 19 patients of neurobrucellosis and they accounted for 8% of all cases of brucellosis admitted to Shiraz University Hospitals over a period of eight years. Headache, fever, fatigue, drowsiness and neck stiffness were the common clinical features. Cerebrospinal fluid (CSF) showed pleocytosis in 100%, elevated protein levels in 89% and low glucose level in 47% of the patients. All the patients improved with specific antibiotic treatment. Of the 19 patients, 10 (52.5%) patients received treatment for 8 to 28 weeks. Duration of antibiotic treatment was: 8-14 weeks in 8 (42%) patients; 24-28 weeks in 2 (10.5%) patients; 6 months in 7 (37%) patients; 12 months in 1 (5.3%) patient; and 18 months in 1 (5.3%) patient. Clinicians in endemic areas should consider the likelihood of neurobrucellosis in patients with unexplained neurological and psychiatric symptoms.
Keywords
Neurobrucellosis, short course, treatment
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