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Papillary tumor of pineal region: Report of three cases and review of literature
Epari, Sridhar; Bashyal, Reeta; Malick, Suman; Gupta, Tejpal; Moyadi, Aliasgar; Kane, S.V.; Bal, Munita & Jalali, Rakesh
Abstract
Papillary tumors of the pineal region (PTPRs) are rare and are recognized as a distinct entity in the recent 2007 World Health Organization (WHO) classification of tumors of nervous system. Till date, only 55 cases have been reported. We report another three patients of PTPRs with characteristic radiological features. Histologically, all the three patients exhibited remarkable uniform histology of epithelioid morphology with variable presence of single to multilayered papillary architecture. Consistent absence of fibrillary matrix was noted in all the three cases. None of the cases showed aggressive histology. A large multicenter study is essential for upfront characterizing the biological behavior, as frequency of these tumors is very low.
Keywords
Fibrillary matrix, papillary architecture, papillary tumors of the pineal region
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