Medknow Publications on behalf of the Neurological Society of India
Vol. 59, No. 5, 2011, pp. 669-673
Bioline Code: ni11208
Full paper language: English
Document type: Research Article
Document available free of charge
Neurology India, Vol. 59, No. 5, 2011, pp. 669-673
© Copyright 2011 Neurology India.
Pilot study on a fast postoperative programming approach to subthalamic nucleus stimulation in Parkinson's disease|
Li, Peng; Mao, Boyong; Shang, Huifang; Kaelin-Lang, Alain & Wang, Wei
Objectives : To evaluate the advantages and disadvantages of a fast post-operative screening method using deep brain stimulation (DBS) of the subthalamic nucleus (STN) in patients with Parkinson's disease.
Materials and Methods: Twenty-four patients implanted with electrodes for STN-DBS were divided into two groups : Group I received traditional programming and Group II was treated with the fast method. The time required for programming in each group and the treatment effects were analyzed.
Results: Significant postoperative improvement of the Unified Parkinson's Disease Rating Scale III was achieved in the "off medication" and "on stimulation" condition in both the groups (Group I: 51.2% vs. Group II: 54.0%, P<0.05). The average time needed for programming, however, was significantly shorter in Group II as compared to Group I (P<0.05).
Conclusions: The new fast method can significantly reduce the time required to find a preliminary effective STN-DBS protocol in the early postoperative phase without sacrificing clinical efficacy.
Deep brain stimulation, Parkinson's disease, subthalamic nucleus
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