About Bioline  All Journals  Testimonials  Membership  News

Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886
EISSN: 0028-3886
Vol. 59, No. 5, 2011, pp. 669-673
Bioline Code: ni11208
Full paper language: English
Document type: Research Article
Document available free of charge

Neurology India, Vol. 59, No. 5, 2011, pp. 669-673

 en Pilot study on a fast postoperative programming approach to subthalamic nucleus stimulation in Parkinson's disease
Li, Peng; Mao, Boyong; Shang, Huifang; Kaelin-Lang, Alain & Wang, Wei


Objectives : To evaluate the advantages and disadvantages of a fast post-operative screening method using deep brain stimulation (DBS) of the subthalamic nucleus (STN) in patients with Parkinson's disease.
Materials and Methods: Twenty-four patients implanted with electrodes for STN-DBS were divided into two groups : Group I received traditional programming and Group II was treated with the fast method. The time required for programming in each group and the treatment effects were analyzed.
Results: Significant postoperative improvement of the Unified Parkinson's Disease Rating Scale III was achieved in the "off medication" and "on stimulation" condition in both the groups (Group I: 51.2% vs. Group II: 54.0%, P<0.05). The average time needed for programming, however, was significantly shorter in Group II as compared to Group I (P<0.05).
Conclusions: The new fast method can significantly reduce the time required to find a preliminary effective STN-DBS protocol in the early postoperative phase without sacrificing clinical efficacy.

Deep brain stimulation, Parkinson's disease, subthalamic nucleus

© Copyright 2011 Neurology India.
Alternative site location:

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2024, Site last up-dated on 01-Sep-2022.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Google Cloud Platform, GCP, Brazil