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Nigerian Journal of Physiological Sciences
Physiological Society of Nigeria
ISSN: 0794-859X
Vol. 17, No. 1-2, 2002, pp. 48-51
Bioline Code: np02009
Full paper language: English
Document type: Research Article
Document available free of charge

Nigerian Journal of Physiological Sciences, Vol. 17, No. 1-2, 2002, pp. 48-51

 en ANTI- HELICOBACTER PYLORI check for this species in other resources EFFECTS OF THE METHANOL EXTRACTS OF Allium ascalonicum check for this species in other resources (LINN.) LILIACEAE) BULB.
ADENIYI, BOLANLE A. AND ANYIAM, F. M.

Abstract

Allium ascalonicum check for this species in other resources bulb of the family Liliaceae is an annual herbaceous plant of smaller size than Allium cepa. The bulb is of considerable importance in African cooking and in salads. Various species have been reported to have anti-diabetic, hypolesterolaemic, fibrinolytic, anti-ulcer and diuretic potentials. Crude methanol extracts of Allium ascalonicum bulb was screened against three strains of Helicobacter pylori check for this species in other resources (UCH 97001, UCH 98026 and UCH 97009) for antibacterial activity by the agar diffusion method on Muller-Hinton agar supplemented with defibrinated house blood and grown in a microaerophilic incubator. All the strains were inhibited by the extract. Further investigation on the effect of the extracts on the urease activity of the Helicabacter pylori strains showed that urease activity of all the strains decreased with increase in the concentration of the extracts. Phytochemical screening of the plant revealed the presence of alkaloids, saponins, cardiac glycosides and essential oils while tannins were not detected. Allium ascalonicum bulb has some therapeutic potential against Hellicobacter pylori, which may be explored by pharmaceutical companies and patients with gastroduodenal disorders.

Keywords
Allium ascalonicum, anti-Helicobacter pylori, urease activity.

 
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