Aotus is one of the WHO-recommended primate models for studies in malaria, and several species can be infected with Plasmodium falciparum
or P. vivax
. Here we describe the successful infection of the species A. infulatus
from eastern Amazon with blood stages of P. falciparum
. Both intact and splenectomized animals were susceptible to infection; the intact ones were able to keep parasitemias at lower levels for several days, but developed complications such as severe anemia; splenectomized monkeys developed higher parasitemias but no major complications. We conclude that A. infulatus
is susceptible to P. falciparum
infection and may represent an alternative model for studies in malaria.