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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 95, No. 3, 2000, pp. 367-373
Bioline Code: oc00060
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 95, No. 3, 2000, pp. 367-373

 en Biological Screening of Brazilian Medicinal Plants
Tnia Maria de Almeida Alves; Andria Fonseca Silva; Mitzi Brando; Telma Sueli Mesquita Grandi; Elza de Ftima A Smnia; Artur Smnia Jnior & Carlos Leomar Zani

Abstract

In this study, we screened sixty medicinal plant species from the Brazilian savanna ("cerrado") that could contain useful compounds for the control of tropical diseases. The plant selection was based on existing ethnobotanic information and interviews with local healers. Plant extracts were screened for: (a) molluscicidal activity against Biomphalaria glabrata check for this species in other resources , (b) toxicity to brine shrimp ( Artemia salina check for this species in other resources L.), (c) antifungal activity in the bioautographic assay with Cladosporium sphaerospermum and (d) antibacterial activity in the agar diffusion assay against Staphylococcus aureus check for this species in other resources , Escherichia coli check for this species in other resources , Bacillus cereus and Pseudomonas aeruginosa. Forty-two species afforded extracts that showed some degree of activity in one or more of these bioassays.

Keywords
medicinal plants, Artemia salina, Biomphalaria glabrata, Cladosporium sphaerospermum, antibacterial activity, Brazil

 
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