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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 95, No. 4, 2000, pp. 591-594
Bioline Code: oc00094
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 95, No. 4, 2000, pp. 591-594

 en Acidic Ribosomal Proteins and Histone H3 from Leishmania Present a High Rate of Divergence
Ysabel Montoya; Carlos Padilla; Maxy De Los Santos; Teresa Barreto; Douglas Barker & Carlos Carrillo

Abstract

Another additional peculiarity in Leishmania will be discussed about of the amino acid divergence rate of three structural proteins: acidic ribosomal P1 and P2b proteins, and histone H3 by using multiple sequence alignment and dendrograms.

These structural proteins present a high rate of divergence regarding to their homologous protein in Trypanosoma cruzi. At this regard, L. (V.) peruviana P1 and T. cruzi P1 showed 57.4% of divergence rate. Likewise, L. (V.) braziliensis histone H3 and acidic ribosomal P2 protein exhibited 31.8% and 41.7% respectively of rate of divergence in comparison with their homologous in T. cruzi.

Keywords
Leishmania, acidic ribosomal proteins, histone H3

 
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