About Bioline  All Journals  Testimonials  Membership  News  Donations

Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 95, No. s1, 2000, pp. 201-206
Bioline Code: oc00182
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 95, No. s1, 2000, pp. 201-206

 en Mosquitocidal Bacterial Toxins: Diversity, Mode of Action and Resistance Phenomena
Jean-François Charles & Christina Nielsen-LeRoux


Bacteria active against dipteran larvae (mosquitoes and black flies) include a wide variety of Bacillus thuringiensis and B. sphaericus strains, as well as isolates of Brevibacillus laterosporus and Clostridium bifermentans. All display different spectra and levels of activity correlated with the nature of the toxins, mainly produced during the sporulation process. This paper describes the structure and mode of action of the main mosquitocidal toxins, in relationship with their potential use in mosquito and/or black fly larvae control. Investigations with laboratory and field colonies of mosquitoes that have become highly resistant to the B. sphaericus Bin toxin have shown that several mechanisms of resistance are involved, some affecting the toxin/receptor binding step, others unknown.

Bacillus thuringiensis, Bacillus sphaericus, Brevibacillus laterosporus, Clostridium bifermentans, toxin binding, receptor, resistance

© Copyright 2000 Fundacao Oswaldo Cruz Fiocruz
Alternative site location:

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2019, Site last up-dated on 16-Oct-2019.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil