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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 96, No. s1, 2001, pp. 103-105
Bioline Code: oc01158
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 96, No. s1, 2001, pp. 103-105

 en Preliminary Results on the Effects of CD40/CD40L Interactions and SAC-induction on IFN-γ Expression in Human Schistosomiasis
Silvia ML Montenegro; Frederico GC Abath; Ana LC Domingues; Wlademir Melo; Clarice NL de Morais; Eridan M Coutinho; Siddhartha Mahanty & Thomas Wynn


In this communication the authors analyzed the pattern of expression of IFN-γ as a surrogate type 1 response in different clinical forms of schistosomiasis in response to stimulation involving T-cell dependent and T-cell independent pathways, to investigate which pathways were functional in human schistosomiasis, and to further characterize the nature of Th1 response impairment in this parasitic disease.

Schistosoma mansoni, CD40/CD40 ligand, human schistosomiasis, IFN-γ

© Copyright 2001 Instituto Oswaldo Cruz - Fiocruz
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