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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 96, No. s1, 2001, pp. 165-167
Bioline Code: oc01169
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 96, No. s1, 2001, pp. 165-167

 en SHORT COMMUNICATION - Replacing Oxamniquine by Praziquantel against Schistosoma mansoni check for this species in other resources Infection in a Rural Community from the Sugar-cane Zone of Northeast Brazil: an Epidemiological Follow-up
Lilian Beck; Tereza Cristina Favre; Otávio Sarmento Pieri; Luciana Carvalho Zani; Glauce Gajo Domas & Constança Simões Barbosa


A group of 52 villagers was followed-up for three years regarding Schistosoma mansoni check for this species in other resources infection. All villagers were periodically surveyed by the Kato-Katz method. In March 1997 and March 1998 the positives were treated with oxamniquine (15-20 mg/kg), and in March 1999, with praziquantel (60 mg/kg). All infection indices decreased substantially between March 1999 and March 2000: prevalence of infection (from 32.7% to 21.2%), prevalence of moderate/heavy infection (from 7.7% to 1.9%), intensity of infection (from 23.1 epg to 7.4 epg) and reinfection (from 35.7% to 14.3%). Negativation increased from 53.8 to 82.4. An optimistic prognostic is assumed in the short term for the introduction of praziquantel in the study area.

schistosomiasis, control, chemotherapy, Northeast, Brazil

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