Leishmania major check for this species in other resources - telomeric terminus - cloning"/>
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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 97, No. 2, 2002, pp. 343-346
Bioline Code: oc02065
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 97, No. 2, 2002, pp. 343-346

 en SHORT COMMUNICATION - Charaterization of Leishmania major check for this species in other resources Friedlin Telomeric Terminus
Miguel Angel Chiurillo & José Luis Ramírez

Abstract

Here we have characterized Leishmania major check for this species in other resources (Friedlin) telomeric terminus (the very end) using recombinants obtained by a vector-adaptor cloning protocol. As in L. donovani, the last nine nucleotides of L. major terminus are 5'-GGTTAGGGT-OH 3', differing from Trypanosoma cruzi check for this species in other resources and T. brucei terminus 5'GGGTTAGGG-OH 3', thus indicating that these sequences are genus specific. We have also made a comparative analysis between L. major and L. donovani telomere-associated sequences, and described a novel non-repeated telomeric associated sequence common to L. major low molecular weight chromosomal bands.

Keywords
Leishmania major check for this species in other resources - telomeric terminus - cloning

 
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