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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 97, No. 4, 2002, pp. 443-457
Bioline Code: oc02087
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 97, No. 4, 2002, pp. 443-457

 en Some Aspects of Protozoan Infections in Immunocompromised Patients - A Review
Marcelo Simão Ferreira & Aércio Sebastião Borges

Abstract

Protozoa are among the most important pathogens that can cause infections in immunocompromised hosts. These microorganisms particularly infect individuals with impaired cellular immunity, such as those with hematological neoplasias, renal or heart transplant patients, patients using high doses of corticosteroids, and patients with acquired immunodeficiency syndrome. The protozoa that most frequently cause disease in immunocompromised patients are Toxoplasma gondii check for this species in other resources , Trypanosoma cruzi check for this species in other resources , different Leishmania species, and Cryptosporidium parvum check for this species in other resources ; the first two species cause severe acute meningoencephalitis and acute myocarditis, Leishmania check for this species in other resources sp. causes mucocutaneous or visceral disease, and Cryptosporidium can lead to chronic diarrhea with hepatobiliary involvement. Various serological, parasitological, histological and molecular methods for the diagnosis of these infections are currently available and early institution of specific therapy for each of these organisms is a basic measure to reduce the morbidity and mortality associated with these infections.

Keywords
protozoa - acquired immunodeficiency syndrome-Aids - opportunistic infections

 
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