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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 97, No. 5, 2002, pp. 643-644
Bioline Code: oc02123
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 97, No. 5, 2002, pp. 643-644

 en SHORT COMMUNICATION - Prevalence of Hepatitis C Virus Infection among Hemophiliacs in Central Brazil
Adriana P Barbosa; Regina MB Martins; Sheila A Teles; Simonne A Silva; Jaqueline M Oliveira & Clara FT Yoshida

Abstract

In order to investigate the hepatitis C virus (HCV) infection prevalence and risk factors in hemophiliacs in Central Brazil, 90 patients were interviewed and serum samples tested for HCV RNA and anti-HCV antibodies. An overall prevalence of 63.3% (CI 95%: 53.0-72.7) was found. Multivariate analysis of risk factors showed that number of blood transfusions was significantly associated with this infection. Most hemophiliacs received locally produced cryoprecipitate. All infected patients were transfused before the screening of blood units for anti-HCV. However, hemophiliacs who received exclusively screened cryoprecipitate were HCV negative. It confirms the expected decline in transfusion-acquired hepatitis C.

Keywords
hepatitis C - hemophilia - prevalence - Central Brazil

 
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