Schistosoma mansoni check for this species in other resources - Biomphalaria glabrata check for this species in other resources - hydrocortisone - sporocyst - hemocyte reaction"/>
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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 97, No. 6, 2002, pp. 881-885
Bioline Code: oc02169
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 97, No. 6, 2002, pp. 881-885

 en The Influence of Hydrocortisone on Cellular Defence Mechanisms of Biomphalaria glabrata check for this species in other resources
Deborah Regina Serrano; Eliana Maria Zanotti-Magalhães; Luiz Augusto Magalhães & José Ferreira de Carvalho

Abstract

Since the internal defense system of mollusks consists of cellular and humoral mechanisms, we examined the role of hydrocortisone in mollusks defense cells and the influence of this steroid on the development of Schistosoma mansoni check for this species in other resources in its intermediary host. Hydrocortisone had an immunosuppressive action in Biomphalaria glabrata check for this species in other resources , as reflected in the reduced number of defense cells and the altered cell physiology. Histopathological analysis showed that hydrocortisone facilitated the intramolluscan development of S. mansoni , by reducing the extent of the inflammatory response, seen as a greater number of viable sporocysts with no surrounding hemocytes.

Keywords
Schistosoma mansoni check for this species in other resources - Biomphalaria glabrata check for this species in other resources - hydrocortisone - sporocyst - hemocyte reaction

 
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