Trypanosoma cruzi check for this species in other resources - "cruzi" complex - genetic diversity"/>
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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 98, No. 1, 2003, pp. 1-12
Bioline Code: oc03031
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 98, No. 1, 2003, pp. 1-12

 en Should Trypanosoma cruzi check for this species in other resources be Called "cruzi" Complex? A Review of the Parasite Diversity and the Potential of Selecting Population after in Vitro Culturing and Mice Infection
Rodolfo Devera; Octavio Fernandes & José Rodrigues Coura

Abstract

Morpho-biological diversity of Trypanosoma cruzi check for this species in other resources has been known since Chagas' first works in 1909. Several further studies confirmed the morphological differences among the parasite strains, which were isolated from different reservoirs and vectors, as well as from human beings. In the early sixties, antigenic differences were found in the parasite strains from various sources. These differences, coupled to the observation of regional variations of the disease, led to the proposal of the term cruzi complex to designate the taxon T. cruzi. Since then this protozoan has been typed in distinct biodemes, zymodemes and lineages which were consensually grouped into T. cruzi I, T. cruzi II and into non-grouped strains. T. cruzi genotypic characterization, initially carried out by schizodeme analysis and more recently by various other techniques, has shown a great diversity of the parasite strains. In fact, T. cruzi is formed by groups of heterogeneous sub-population, which present specific characteristics, including distinct histotropism. The interaction of the different infecting clones of the cruzi complex and the human host will determine the morbidity of the disease.

Keywords
Trypanosoma cruzi check for this species in other resources - "cruzi" complex - genetic diversity

 
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