Trypanosoma cruzi check for this species in other resources - interspersed repetitive DNA - transcription - retroelement insertion - subtelomeric region"/>
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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 98, No. 1, 2003, pp. 129-133
Bioline Code: oc03046
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 98, No. 1, 2003, pp. 129-133

 en SHORT COMMUNICATION - A Novel Reiterated Family of Transcribed Oligo(A)-terminated, Interspersed DNA Elements in the Genome of Trypanosoma cruzi check for this species in other resources
Newton Valério Verbisck; Márcia Regina Machado dos Santos; David M Engman; Miguel Angel Chiurillo; José Luis Ramirez; Jorge Enrique Araya; Renato Arruda Mortara & José Franco da Silveira

Abstract

We report the molecular characterization of a novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of Trypanosoma cruzi check for this species in other resources . Steady-state level of transcripts of this sequence family appeared to be developmentally regulated, since only in the replicative forms the parasite showed expression of related sequences with a major band around 3 kb. The presence of frame shifts or premature stop codons predicts that transcripts are not translated. The sequence family also contains truncated forms of retrotransposons elements that may become potential hot spots for retroelement insertion. Sequences homologous to this family are interspersed at many chromosomes including the subtelomeric regions.

Keywords
Trypanosoma cruzi check for this species in other resources - interspersed repetitive DNA - transcription - retroelement insertion - subtelomeric region

 
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