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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 98, No. 2, 2003, pp. 273-276
Bioline Code: oc03067
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 98, No. 2, 2003, pp. 273-276

 en SHORT COMMUNICATION - Perspective of a New Diagnostic for Human Trichomonosis
Sheila B Lecke; Tiana Tasca; André A Souto & Geraldo A De Carli

Abstract

Several diagnostic techniques have been employed for the detection of Trichomonas vaginalis check for this species in other resources . Microtubules constitute the cytoskeleton in eukaryotic cells and are sensitive to antimitotic drugs, such as Taxol (paclitaxel). We used FLUTAX a fluorescent taxoid - to analyze the microtubule distribution in living trophozoites of T. vaginalis in urine and in vaginal discharge. A high intensity of fluorescence was observed in living T. vaginalis , epithelial cells and leukocytes present in urine and vaginal discharge. Our preliminary results show the perspective of a new diagnostic technique for trichomonosis and will contribute to the understanding of the cytoskeleton of T. vaginalis .

Keywords
Trichomonas vaginalis check for this species in other resources - diagnostic techniques - FLUTAX

 
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