Leishmania (V.) braziliensis check for this species in other resources - small chromosome - genomic amplification"/>
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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 98, No. 3, 2003, pp. 377-378
Bioline Code: oc03084
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 98, No. 3, 2003, pp. 377-378

 en SHORT COMMUNICATION - The 245 kb Amplified Chromosome of Leishmania (V.) braziliensis Contains a Biopterin Transporter Gene
MCR Sampaio & YM Traub-Cseko

Abstract

Leishmania (V.) braziliensis M2903 presents a small linear and stable 245 kb chromosome originating from a genomic amplification. Similar amplifications present in other species of Leishmania check for this species in other resources contain a gene coding for a biopterin transporter. Since Leishmania is auxotrophic for this metabolite, this amplification could result from the need to better capture biotpterin from growth media under specific circumstances. In this paper we show that this gene is also present in L. (V.) braziliensis small chromosome, which shares sequences with other genomic amplifications already described.

Keywords
Leishmania (V.) braziliensis check for this species in other resources - small chromosome - genomic amplification

 
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