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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 98, No. 3, 2003, pp. 401-405
Bioline Code: oc03090
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 98, No. 3, 2003, pp. 401-405

 en Species Distribution and Antifungal Susceptibility Profile of Candida check for this species in other resources spp. Bloodstream Isolates from Latin American Hospitals
Patrício Godoy; Iris Nora Tiraboschi; Luiz Carlos Severo; Beatriz Bustamante; Belinda Calvo; Leila Paula de Almeida; Daniel Archimedes da Matta & Arnaldo Lopes Colombo

Abstract

From March 1999 to March 2000, we conducted a prospective multicenter study of candidemia involving five tertiary care hospitals from four countries in Latin America. Yeast isolates were identified by classical methods and the antifungal susceptibility profile was determined according to the National Committee for Clinical Laboratory Standards microbroth assay method.

During a 12 month-period we were able to collect a total of 103 bloodstream isolates of Candida check for this species in other resources spp. C. albicans was the most frequently isolated species accounting for 42% of all isolates. Non-albicans Candida species strains accounted for 58% of all episodes of candidemia and were mostly represented by C. tropicalis (24.2%) and C. parapsilosis (21.3%). It is noteworthy that we were able to identify two cases of C. lusitaniae from different institutions. In our casuistic, non-albicans Candida species isolates related to candidemic episodes were susceptible to fluconazole. Continuously surveillance programs are needed in order to identify possible changes in the species distribution and antifungal susceptibility patterns of yeasts that may occurs after increasing the use of azoles in Latin American hospitals.

Keywords
candidemia - antifungal susceptibility - Candida check for this species in other resources spp.

 
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