Swartzia langsdorffii check for this species in other resources - Leguminosae - chemotaxonomy - saponins - molluscicidal activity - schistosomiasis - Artemia salina check for this species in other resources "/>
search
for
 About Bioline  All Journals  Testimonials  Membership  News  Donations


Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 98, No. 5, 2003, pp. 713-718
Bioline Code: oc03146
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 98, No. 5, 2003, pp. 713-718

 en Saponins from Swartzia langsdorffii check for this species in other resources : Biological Activities
Aderbal Farias Magalhães; Ana Maria Goulart de Azevedo Tozzi; Celira Caparica Santos; Deborah Regina Serrano; Eliana Maria Zanotti-Magalhães; Eva Gonçalves Magalhães & Luiz Augusto Magalhães

Abstract

The presence of saponins and the molluscicidal activity of the roots, leaves, seeds and fruits of Swartzia langsdorffii check for this species in other resources Raddi (Leguminosae) against Biomphalaria glabrata check for this species in other resources adults and eggs were investigated. The roots, seeds and fruits were macerated in 95% ethanol. These extracts exerted a significant molluscicidal activity against B. glabrata, up to a dilution of 100 mg/l. Four mixtures (A2, B2, C and D) of triterpenoid oleanane type saponins were chromatographically isolated from the seed and fruit extracts. Two known saponins (1 and 2) were identified as β-D-glucopyranosyl-[α-L-rhamnopyranosyl-(1→3)- β-D-glucuronopyranosyl-(1→3)]-3β-hydroxyolean-12-ene-28 -oate, and β-D-glucopyranosyl-(1→3)-β-D-glucuronopyranosyl-(1 →3)]-3β-hydroxyolean-12-ene-28-oate, respectively. These two saponins were present in all the mixtures, together with other triterpenoid oleane type saponins, which were shown to be less polar, by reversed-phase HPLC. The saponin identifications were based on spectral evidence, including 1H-1H two-dimensional correlation spectroscopy, nuclear Overhauser and exchange spectroscopy, heteronuclear multiple quantum coherence, and heteronuclear multiple-bond connectivity experiments. The toxicity of S. langsdorffii saponins to non-target organisms was prescreened by the brine shrimp lethality test.

Keywords
Swartzia langsdorffii check for this species in other resources - Leguminosae - chemotaxonomy - saponins - molluscicidal activity - schistosomiasis - Artemia salina check for this species in other resources

 
© Copyright 2003 - Instituto Oswaldo Cruz - Fiocruz
Alternative site location: http://memorias.ioc.fiocruz.br

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2017, Site last up-dated on 16-Oct-2017.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil