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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 98, No. 6, 2003, pp. 823-825
Bioline Code: oc03165
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 98, No. 6, 2003, pp. 823-825

 en SHORT COMMUNICATION - Antibody Isotype Responses in Balb/c Mice Immunized with the Cytoplasmic Repetitive Antigen and Flagellar Repetitive Antigen of Trypanosoma cruzi check for this species in other resources
Valéria RA Pereira; Virginia Maria B Lorena; Alinne Fernanda A Verçosa; Edmilson D Silva; Antonio GP Ferreira; Ulisses R Montarroyos; Ana P Galvão Silva & Yara M Gomes

Abstract

In the present report we analyzed the levels of IgG1, IgG2a, IgG2b and IgG3 isotypes from Balb/c mice immunized with cytoplasmic repetitive antigen (CRA), and flagelar repetitive antigen (FRA) of Trypanosoma cruzi. The immunization was done by subcutaneous route three times (20 days apart) and the analysis was performed 14 days after each treatment. CRA-immunized mice produced high levels of all IgG isotypes, mainly IgG3 and IgG1. FRA-immunization elicited only high levels of IgG1.

Keywords
Trypanosoma cruzi check for this species in other resources - recombinant antigens - immunization - isotypes

 
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