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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 99, No. 1, 2004, pp. 81-83
Bioline Code: oc04014
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 99, No. 1, 2004, pp. 81-83

 en Short Communication - Detection of Cytotoxic Necrotizing Factor Types 1 and 2 among Fecal Escherichia coli check for this species in other resources Isolates from Brazilian Children with and without Diarrhea
Ana Terezinha Tavechio; Lilian Regina M Marques; Cecília Mari Abe & Tânia AT Gomes

Abstract

The enteropathogenic role of cytotoxic necrotizing factor (CNF)-producing Escherichia coli check for this species in other resources was investigated by searching cnf genes among 2074 isolates from 200 children with and 200 without acute diarrhea in Brazil. Fourteen (7%) cases versus 10 (5%) control children carried at least one cnf positive isolate (P = 0.50) and most isolates expressed CNF type 1. DNA sequences of virulence factors of extraintestinal pathogenic E. coli (ExPEC) were detected in 78.6% of CNF1-producing isolates. Besides not being associated with human acute diarrhea, the CNF1-producing isolates here identified may represent potential ExPEC transitorily composing the normal intestinal flora.

Keywords
Escherichia coli check for this species in other resources - cytotoxins - cytotoxic necrotizing factor - adhesins

 
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