Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
Vol. 99, No. 3, 2004, pp. 281-282
Bioline Code: oc04050
Full paper language: English
Document type: Research Article
Document available free of charge
Memórias do Instituto Oswaldo Cruz, Vol. 99, No. 3, 2004, pp. 281-282
© Copyright 2004 - Instituto Oswaldo Cruz - Fiocruz.
SHORT COMMUNICATION - Prevalence of Human Papillomavirus Type 16 Variants in the Federal District, Central Brazil|
Márcio R Cruz; Daniela M Cerqueira; Waldenor B Cruz; Geni NL Camara; Marcelo M Brígido; Evandro O Silva; Luciano GS Carvalho & Cláudia RF Martins
We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma.
human papillomavirus type 16 - variants - Federal District, Brazil
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