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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 99, No. s1, 2004, pp. 97-98
Bioline Code: oc04094
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 99, No. s1, 2004, pp. 97-98

 en SHORT COMMUNICATION - Evaluation of Tests Based on the Antibody Response to Keyhole Limpet Haemocyanin and Soluble Egg Antigen to Differentiate Acute and Chronic Human Schistosomiasis Mansoni
Lílian Beck; Daniele SM Van-Lüme; Joelma R de Souza; Clarice N Lins de Morais; Wlademir G Melo; Edeneide Xavier; Constança S Barbosa; Marcílio L Aroucha; Ana Lúcia C Domingues; Tereza Favre; Otávio Pieri; Frederico GC Abath & Silvia ML Montenegro

Abstract

Specific IgG and IgM responses to soluble egg antigen (SEA) and keyhole limpet haemocyanin (KLH) were measured by ELISA in patients with acute and chronic schistosomiasis. The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in conjunction with clinical and epidemiological data to the differential diagnosis of acute schistosomiasis.

Keywords
keyhole limpet haemocyanin - soluble egg antigens - enzime-linked immunosorbent assay

 
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