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SHORT COMMUNICATION - Evaluation of Tests Based on the Antibody Response to Keyhole Limpet Haemocyanin and Soluble Egg Antigen to Differentiate Acute and Chronic Human Schistosomiasis Mansoni Lílian Beck; Daniele SM Van-Lüme; Joelma R de Souza; Clarice N Lins de Morais; Wlademir G Melo; Edeneide Xavier; Constança S Barbosa; Marcílio L Aroucha; Ana Lúcia C Domingues; Tereza Favre; Otávio Pieri; Frederico GC Abath & Silvia ML Montenegro Abstract Specific IgG and IgM responses to soluble egg antigen (SEA) and keyhole limpet haemocyanin (KLH) were measured by ELISA in patients with acute and chronic schistosomiasis. The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in conjunction with clinical and epidemiological data to the differential diagnosis of acute schistosomiasis. Keywords keyhole limpet haemocyanin - soluble egg antigens - enzime-linked immunosorbent assay

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