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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 99, No. 6, 2004, pp. 575-576
Bioline Code: oc04122
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 99, No. 6, 2004, pp. 575-576

 en SHORT COMMUNICATION - Study of Hantavirus Infection in Captive Breed Colonies of Wild Rodents
RC Oliveira; T Rozental; AA Alves-Corrêa; PS D'Andrea; HG Schatzmayr & R Cerqueira ERS Lemos

Abstract

Wild sigmondontine rodents are known to be the reservoir of several serotypes of New World hantaviruses. The mechanism of viral transmission is by aerosol inhalation of the excreta from infected rodents. Considering that the captive breed colonies of various wild mammals may present a potencial risk for hantaviral transmission, we examined 85 speciemens of Thrichomys check for this species in other resources spp. (Echimyidae) and 17 speciemens of Nectomys squamipes check for this species in other resources (Sigmodontinae) from our colony for the presence of hantavirus infections. Blood samples were assayed for the presence of antibodies to Andes nucleocapsid antigen using enzyme-linked immunosorbent assay (ELISA). Additionally, serum samples from workers previously exposed to wild rodents, in the laboratories where the study was conducted, were also tested by ELISA to investigate prevalence of anti-hantavirus IgG antibodies. All blood samples were negative for hantavirus antibodies. Although these results suggest that those rodent's colonies are hantavirus free, the work emphasizes the need for hantavirus serological monitoring in wild colonized rodents and secure handling potentially infected rodents as important biosafety measures.

Keywords
hantaviruses - rodents - hantavirus cardiopulmonary syndrome (HPS)

 
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