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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 99, No. 6, 2004, pp. 581-589
Bioline Code: oc04124
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 99, No. 6, 2004, pp. 581-589

 en Biologic Data of Macaca mulatta check for this species in other resources , Macaca fascicularis check for this species in other resources , and Saimiri sciureus check for this species in other resources Used for Research at the Fiocruz Primate Center
Márcia Cristina Ribeiro Andrade; Carlos Torres Ribeiro; Virgílio Ferreira da Silva; Etelcia Moraes Molinaro; Miguel Ângelo Brück Gonçalves; Marcos Antônio Pereira Marques; Pedro Hernan Cabello & José Paulo Gagliardi Leite

Abstract

Physiological parameters of laboratory animals used for biomedical research is crucial for following several experimental procedures. With the intent to establish baseline biologic parameters for non-human primates held in closed colonies, hematological and morphometric data of captive monkeys were determined. Data of clinically healthy rhesus macaques ( Macaca mulatta check for this species in other resources ), cynomolgus monkeys ( Macaca fascicularis check for this species in other resources ), and squirrel monkeys ( Saimiri sciureus check for this species in other resources ) were collected over a period of five years. Animals were separated according to sex and divided into five age groups. Hematological data were compared with those in the literature by Student's t test. Discrepancies with significance levels of 0.1, 1 or 5% were found in the hematological studies. Growth curves showed that the sexual dimorphism of rhesus monkeys appeared at an age of four years. In earlier ages, the differences between sexes could not be distinguished (p < 0.05). Sexual dimorphism in both squirrel monkeys and cynomolgus monkeys occurred at an age of about 32 months. Data presented in this paper could be useful for comparative studies using primates under similar conditions.

Keywords
non-human primates - growth curve - hematological parameters - biologic data - biometry

 
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