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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 99, No. 7, 2004, pp. 717-720
Bioline Code: oc04145
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 99, No. 7, 2004, pp. 717-720

 en SHORT COMMUNICATION - Alteration in the Endogenous Intestinal Flora of Swiss Webster Mice by Experimental Angiostrongylus costaricensis Infection
Vandack Nobre; José Carlos Serufo; Omar dos Santos Carvalho; Cristiane Lafetá Gomes Furtado Mendonça; Simone Gonçalves Santos; Ester Maria Mota; Daniel Gomes; Emanuella Braga; Carlos Maurício Figueiredo Antunes; Henrique Leonel Lenzi & José Roberto Lambertucci


The association between worm infections and bacterial diseases has only recently been emphasized. This study examined the effect of experimental Angiostrongylus costaricensis infection on endogenous intestinal flora of Swiss Webster mice. Eight mice aging six weeks were selected for this experiment. Four were infected with A. costaricensis and the other four were used as controls. Twenty eight days after the worm infection, all mice in both groups were sacrificed and samples of the contents of the ileum and colon were obtained and cultured for aerobic and anaerobic bacteria. In the mice infected with A. costaricensis there was a significant increase in the number of bacteria of the endogenous intestinal flora, accompanied by a decrease in the number of Peptostreptococcus spp. This alteration in the intestinal flora of mice infected by the nematode may help to understand some bacterial infections described in humans.

Angiostrongylus costaricensis - intestinal flora - Peptostreptococcus

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