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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 100, No. 3, 2005, pp. 273-275
Bioline Code: oc05082
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 100, No. 3, 2005, pp. 273-275

 en Short Communication - Genetic characterization of Trypanosoma cruzi check for this species in other resources natural clones from the state of Paraíba, Brazil
Christian Barnabé; M Tibayrenc & Carlos Brisola Marcondes

Abstract

Eighteen Trypanosoma cruzi check for this species in other resources stocks from the state of Paraíba, Brazil, isolated from man, wild mammals, and triatomine bugs were studied by multilocus enzyme electrophoresis and random primed amplified polymorphic DNA. Despite the low number of stocks, a notable genetic, genotypic, and phylogenetic diversity was recorded. The presence of the two main phylogenetic subdivisions, T. cruzi I and II, was recorded. The strong linkage disequilibrium observed in the population under survey suggests that T. cruzi undergoes predominant clonal evolution in this area too, although this result should be confirmed by a broader sample. The pattern of clonal variation does not suggests a recent origin by founder effect with a limited number of different genotypes.

Keywords
Trypanosoma cruzi - Triatoma pseudomaculata - Triatoma brasiliensis - Didelphis albiventris - multilocus enzyme electrophoresis - random primed amplified polymorphic DNA - Chagas disease - Paraíba - Brazil

 
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