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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 101, No. 1, 2006, pp. 3-8
Bioline Code: oc06002
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 101, No. 1, 2006, pp. 3-8

 en Physiological changes in Biomphalaria glabrata check for this species in other resources Say, 1818 (Pulmonata: Planorbidae) caused by sub-lethal concentrations of the latex of Euphorbia splendens check for this species in other resources var. hislopii N.E.B (Euphorbiaceae)
Clélia Christina Mello-Silva; Maurício Carvalho de Vasconcellos; Jairo Pinheiro & Maria de Lurdes de Azevedo Rodrigues

Abstract

Molluscides have been used as one of the strategies to control schistosomiasis. Many plant extracts with molluscidal effects have been tested, but the action of the latex of Euphorbia splendens check for this species in other resources var. hislopii is considered the most promising because it meets the recommendations of the World Health Organization (WHO). The objective of this study was to determine the lethal dose and identify the effects of the different doses of latex of E. splendens var. hislopii on the physiology of Biomphalaria glabrata check for this species in other resources submitted to treatment for 24 h. The concentrations of glucose, uric acid and total proteins in the hemolymph and of glycogen in the digestive gland and cephalopodal mass were determined. The LD50 value was 1 mg/l. The highest escape index was found to be at a concentration of 0.6 mg/l. The results showed that the latex of E. splendens var. hislopii caused a sharp reduction in the reserves of glycogen in the digestive gland and elevation of the protein content in the hemolymph of B. glabrata.

Keywords
plant molluscide - Euphorbia splendens var. hislopii - Biomphalaria glabrata

 
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