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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 101, No. 4, 2006, pp. 387-390
Bioline Code: oc06069
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 101, No. 4, 2006, pp. 387-390

 en Synergism between plant extract and antimicrobial drugs used on Staphylococcus aureus check for this species in other resources diseases
Joyce Elaine Cristina Betoni; Rebeca Passarelli Mantovani; Lidiane Nunes Barbosa; Luiz Claudio Di Stasi & Ary Fernandes Junior

Abstract

Searches for substances with antimicrobial activity are frequent, and medicinal plants have been considered interesting by some researchers since they are frequently used in popular medicine as remedies for many infectious diseases. The aim of this study was to verify the synergism between 13 antimicrobial drugs and 8 plant extracts-"guaco" ( Mikania glomerata check for this species in other resources ), guava ( Psidium guajava check for this species in other resources ), clove ( Syzygium aromaticum check for this species in other resources ), garlic ( Allium sativum check for this species in other resources ), lemongrass ( Cymbopogon citratus check for this species in other resources ), ginger ( Zingiber officinale check for this species in other resources ), "carqueja" ( Baccharis trimera check for this species in other resources ), and mint ( Mentha piperita check for this species in other resources ) - against Staphylococcus aureus check for this species in other resources strains, and for this purpose, the disk method was the antimicrobial susceptibility test performed. Petri dishes were prepared with or without dilution of plant extracts at sub-inhibitory concentrations in Mueller-Hinton Agar (MHA), and the inhibitory zones were recorded in millimeters. In vitro anti-Staphylococcus aureus activities of the extracts were confirmed, and synergism was verified for all the extracts; clove, guava, and lemongrass presented the highest synergism rate with antimicrobial drugs, while ginger and garlic showed limited synergistic capacity.

Keywords
medicinal plants - Staphylococcus aureus - antimicrobial drugs - synergism - Kirby & Bauer method

 
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