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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 101, No. 6, 2006, pp. 581-584
Bioline Code: oc06099
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 101, No. 6, 2006, pp. 581-584

 en Detection of Mycobacterium tuberculosis in sputum from Suruí Indian subjects, Brazilian Amazon
Paulo Cesar Basta; Maraníbia AC Oelemann; Walter MR Oelemann; Leila de Souza Fonseca & Carlos EA Coimbra Jr

Abstract

This investigation aimed at the detection of Mycobacterium tuberculosis (MTB) in the sputum of Suruí Indian subjects from Amazonia, Brazil. Polymerase chain reaction analyses were positive for 12 samples, five of which were also culture-positive (N = 147). Four MTB genotypes were identified, one of which showed resistance to rifampicin and isoniazid. The study also highlighted one village complex as of particular importance, considering the relatively high number of tuberculosis cases reported and of MTB isolates obtained.

Keywords
tuberculosis - epidemiology - drug resistance - South American Indians - genotyping

 
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