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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 101, No. s1, 2006, pp. 145-148
Bioline Code: oc06181
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 101, No. s1, 2006, pp. 145-148

 en Molecular approaches for the detection of Schistosoma mansoni check for this species in other resources : possible applications in the detection of snail infection, monitoring of transmission sites, and diagnosis of human infection
Frederico GC Abath; Ana Lisa do Vale Gomes; Fábio L Melo; Constança S Barbosa & Roberto P Werkhauser

Abstract

The detection of specific DNA sequences by polymerase chain reaction (PCR) has proved extremely valuable for the analysis of genetic disorders and the diagnosis of a variety of infectious disease pathogens. However, the application to the detection of Schistosoma mansoni check for this species in other resources is rare, despite a recommendation of the World Health Organization that a major focus of research on schistosomiasis should be on the development and evaluation of new strategies and tools for control of the disease. In this context, a few studies were published for the detection of the parasite in snails, monitoring of cercariae in water bodies, and diagnosis of human infection. The present minireview describes sensitive and specific PCR based systems to detect S. mansoni, indicating possible applications in the detection of snail infection, monitoring of transmission sites, and diagnosis of human infection.

Keywords
polymerase chain reaction - molecular diagnosis - schistosomiasis - transmission - snail - Schistosoma

 
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