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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 102, No. 3, 2007, pp. 245-254
Bioline Code: oc07045
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 102, No. 3, 2007, pp. 245-254

 en The genetic diversity of Plasmodium vivax check for this species in other resources - A Review
de Souza-Neiras, Wanessa Christina; de Melo, Luciane Moreno Storti & Machado, Ricardo Luiz Dantas

Abstract

The genetic diversity of Plasmodium vivax check for this species in other resources has been investigated in several malaria-endemic areas, including the Brazilian Amazon region, where this is currently the most prevalent species causing malaria in humans. This review summarizes current views on the use of molecular markers to examine P. vivax populations, with a focus on studies performed in Brazilian research laboratories. We emphasize the importance of phylogenetic studies on this parasite and discuss the perspectives created by our increasing understanding of genetic diversity and population structure of this parasite for the development of new control strategies, including vaccines, and more effective drugs for the treatment of P. vivax malaria.

Keywords
malaria - Plasmodium vivax - genetic diversity - molecular markers - phylogeny - evolution

 
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