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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 102, No. 6, 2007, pp. 681-685
Bioline Code: oc07109
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 102, No. 6, 2007, pp. 681-685

 en Antimicrobial activity of wax and hexane extracts from Citrus spp. peels
Johann, Susana; de Oliveira, Vetúria Lopes; Pizzolatti, Moacir G; Schripsema, Jan; Braz-Filho, Raimundo; Branco, Alexsandro & Smânia Jr, Artur

Abstract

Antibacterial and antifungal properties of wax and hexane extracts of Citrus spp. peels were tested using bioautographic and microdilution techniques against three plant pathogenic fungi ( Penicillium digitatum check for this species in other resources , Curvularia sp., and Colletotrichum sp.), two human pathogens ( Trichophyton mentagrophytes check for this species in other resources and Microsporum canis check for this species in other resources ), and two opportunistic bacteria ( Escherichia coli check for this species in other resources and Staphylococcus aureus check for this species in other resources ). Two polymethoxylated flavonoids and a coumarin derivative, were isolated and identified from peel extracts, which presented antimicrobial activity especially against M. canis and T. mentagrophytes: 4',5,6,7,8-pentamethoxyflavone (tangeritin) and 3',4',5,6,7,8-hexamethoxyflavone (nobiletin) from C. reticulata; and 6,7-dimethoxycoumarin (also known as escoparone, scoparone or scoparin) from C. limon.

Keywords
polymethoxylated flavonoids - antibiosis - pathogens - fungi - bacteria

 
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