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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 102, No. 7, 2007, pp. 879-882
Bioline Code: oc07158
Full paper language: English
Document type: Short Communication
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 102, No. 7, 2007, pp. 879-882

 en A preliminary analysis of the population genetics and molecular phylogenetics of Onchocerca volvulus check for this species in other resources (Nematoda: Filarioidea) using nuclear ribosomal second internal transcribed spacer sequences
Morales-Hojas, Ramiro; Cheke, Robert A. & Post, Rory J.


Nuclear internal transcribed spacer 2 (ITS2) rDNA sequences were used for a molecular phylogenetics analysis of five Onchocerca species. The sister species of the human parasite O. volvulus was found to be the cattle parasite O. ochengi and not O. gibsoni, contrary to chromosomal evidence. The genetic differentiation of two African populations (representing the two African strains) and a Brazilian population of O. volvulus was also studied. Phylogenetic and network reconstruction did not show any clustering of ITS2 alleles on geographic or strain grounds. Furthermore, population genetics tests showed no indication of population differentiation but suggested gene flow among the three populations.

Onchocerca volvulus - onchocerciasis - strains - molecular phylogenetics - population differentiation

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