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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060 EISSN: 1678-8060
Vol. 104, No. 4, 2009, pp. 665-667
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Bioline Code: oc09149
Full paper language: English
Document type: Short Communication
Document available free of charge
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Memórias do Instituto Oswaldo Cruz, Vol. 104, No. 4, 2009, pp. 665-667
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Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil
Costa, Solange do PSE; Lazéra, Márcia dos S; Santos, Wallace RA; Morales, Bernardina P; Bezerra, Cláudia CF; Nishikawa, Marília M; Barbosa, Gláucia G; Trilles, Luciana; do Nascimento, José LM & Wanke, Bodo
Abstract
The presence of human papillomavirus (HPV) was evaluated in 65 samples of prostate tumours and six samples of prostates with benign prostatic hyperplasia from individuals from Northern Brazil. We used a highly sensitive test, the Linear Array HPV Genotyping Test, to detect 37 high and low-risk HPV types. In this study, only 3% of tumour samples showed HPV infection. Our findings support the conclusion that, despite the high incidence of HPV infection in the geographic regions studied, HPV was not associated with a higher risk of prostate cancer. To our knowledge, this is the first study evaluating the frequency of HPV detection in prostatic tissue of individuals from Brazil.
Keywords
human papillomavirus - prostate cancer - benign prostate hyperplasia
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