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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 104, No. 5, 2009, pp. 678-682
Bioline Code: oc09153
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 104, No. 5, 2009, pp. 678-682

 en Marine Pseudomonas putida check for this species in other resources : a potential source of antimicrobial substances against antibiotic-resistant bacteria
Marinho, Palloma Rodrigues; Moreira, Ana Paula Barbosa; Pellegrino, Flávia Lúcia Piffano Costa; Muricy, Guilherme; Bastos, Maria do Carmo de Freire; dos Santos, Kátia Regina Netto; Giambiagi-deMarval, Marcia & Laport, Marinella Silva

Abstract

Bacteria isolated from marine sponges found off the coast of Rio de Janeiro, Brazil, were screened for the production of antimicrobial substances. We report a new Pseudomonas putida check for this species in other resources strain (designated P. putida Mm3) isolated from the sponge Mycale microsigmatosa check for this species in other resources that produces a powerful antimicrobial substance active against multidrug-resistant bacteria. P. putida Mm3 was identified on the basis of 16S rRNA gene sequencing and phenotypic tests. Molecular typing for Mm3 was performed by RAPD-PCR and comparison of the results to other Pseudomonas strains. Our results contribute to the search for new antimicrobial agents, an important strategy for developing alternative therapies to treat infections caused by multidrug-resistant bacteria.

Keywords
antimicrobial substance - Pseudomonas putida - sponge-associated bacteria

 
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