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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 104, No. 5, 2009, pp. 797-800
Bioline Code: oc09174
Full paper language: English
Document type: Short Communication
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 104, No. 5, 2009, pp. 797-800

 en Performance levels of four Latin American laboratories for the serodiagnosis of Chagas disease in Mexican sera samples
Luquetti, Alejandro O; Espinoza, Bertha; Martínez, Ignacio; Hernández-Becerril, Nidia; Ponce, Carlos; Ponce, Elisa; Reyes, Pedro A; Hernández, Oscar; López, Ruth & Monteón, Victor

Abstract

In nearly all of the previous multicentre studies evaluating serological tests for Trypanosoma cruzi check for this species in other resources infection, sera samples from Central or South American countries have been used preferentially. In this work we compared the reliability of the serological tests using Mexican sera samples that were evaluated in four independent laboratories. This included a reference laboratory in Brazil and three participant laboratories, including one in Central America and two in Mexico. The kappa index between Brazilian and Honduran laboratories reached 1.0 and the index for the Mexican laboratories reached 0.94. Another finding of this study was that the source of antigen did not affect the performance of the serological tests.

Keywords
Trypanosoma cruzi - Chagas disease - serological tests - blood donors - Mexican strains

 
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