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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 104, No. 6, 2009, pp. 813-817
Bioline Code: oc09177
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 104, No. 6, 2009, pp. 813-817

 en Larvicidal activity of extracts from three Plumbago check for this species in other resources spp against Anopheles gambiae check for this species in other resources
Maniafu, Barasa M; Wilber, Lwande; Ndiege, Isaiah O; Wanjala, Cornelius C & Akenga, Teresa Ayuko

Abstract

Three Plumbago check for this species in other resources spp have been tested for mosquito larvicidal activity. The crude extracts exhibiting the highest larvicidal activity against Anopheles gambiae check for this species in other resources were hexane (LC50 = 6.4 μg/mL) and chloroform (LC50 = 6.7 μg/mL) extracts from Plumbago zeylanica check for this species in other resources Linn, chloroform (LC50 = 6.7 ug/mL) extract from Plumbago stenophylla check for this species in other resources Bull and ethyl acetate (LC50 = 4.1 μg/mL) extract from Plumbago dawei Rolfe. These LC50 values were within 95% confidence limits. 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin) 1 (LC50 = 1.9 μg/mL) and β-sitosterol 2 were characterised from ethyl acetate extract of root bark of P. dawei, a native medicinal plant growing in Kenya, based on spectral analysis and comparisons with data in literature.

Keywords
Plumbago zeylanica - Plumbago stenophylla - Plumbago dawei - larvicidal activity - 5-hydroxy-2-methyl-1,4-naphthoquinone - Anopheles gambiae

 
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