Twenty-eight
Klebsiella pneumoniae
clinical isolates that exhibited an extended-spectrum cephalosporin-resistance profile from a city in the Northeast of Brazil were analysed by PCR and DNA sequencing in order to determine the occurrence of
blaCTX-M genes and class 1 integrons. We determined the occurrence of the
blaCTX-M-2 gene in six
K. pneumoniae isolates and describe the first detection of the
blaCTX-M-28 gene in South America. Seven isolates carried class 1 integrons. Partial sequencing analysis of the 5’-3’CS variable region in the class 1 integrons of three isolates revealed the presence of
aadA1, blaOXA-2 and
dfr22 gene cassettes.
