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First report of the blaOXA-58 gene in a clinical isolate of Acinetobacter baumannii in Rio de Janeiro, Brazil de Figueiredo, Deuseli Quaresma; dos Santos, Kátia Regina Netto; Pereira, Eliezer Menezes; Schuenck, Ricardo Pinto; de Mendonça-Souza, Cláudia Rezende Vieira; Teixeira, Lúcia Martins & de Mondino, Silvia Susana Bona Abstract Carbapenemase production is an important mechanism of carbapenem resistance among nonfermentative Gram-negative isolates. This study aimed to report the detection of blaOXA-58 gene in multiresistant clinical isolates of Acinetobacter baumannii recovered from inpatients in a public hospital. Polymerase chain reaction tests were performed to detect the blaOXA-23-like, blaOXA-24-like, blaOXA-58-like and blaOXA-51-like genes. The blaOXA-58 and blaOXA-23 genes were detected in one and three isolates, respectively. Sequencing of the blaOXA-58-like amplicon revealed 100% identity with the A. baumannii blaOXA-58 gene listed in the GenBank database. This is the first report of an OXA-58-producing A. baumannii isolate in Rio de Janeiro, Brazil. Keywords Acinetobacter baumannii - oxacillinases - OXA-58

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