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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 106, No. 3, 2011, pp. 368-370
Bioline Code: oc11061
Full paper language: English
Document type: Short Communication
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 106, No. 3, 2011, pp. 368-370

 en First report of the blaOXA-58 gene in a clinical isolate of Acinetobacter baumannii in Rio de Janeiro, Brazil
de Figueiredo, Deuseli Quaresma; dos Santos, Kátia Regina Netto; Pereira, Eliezer Menezes; Schuenck, Ricardo Pinto; de Mendonça-Souza, Cláudia Rezende Vieira; Teixeira, Lúcia Martins & de Mondino, Silvia Susana Bona

Abstract

Carbapenemase production is an important mechanism of carbapenem resistance among nonfermentative Gram-negative isolates. This study aimed to report the detection of blaOXA-58 gene in multiresistant clinical isolates of Acinetobacter baumannii recovered from inpatients in a public hospital. Polymerase chain reaction tests were performed to detect the blaOXA-23-like, blaOXA-24-like, blaOXA-58-like and blaOXA-51-like genes. The blaOXA-58 and blaOXA-23 genes were detected in one and three isolates, respectively. Sequencing of the blaOXA-58-like amplicon revealed 100% identity with the A. baumannii blaOXA-58 gene listed in the GenBank database. This is the first report of an OXA-58-producing A. baumannii isolate in Rio de Janeiro, Brazil.

Keywords
Acinetobacter baumannii - oxacillinases - OXA-58

 
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