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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 106, No. 6, 2011, pp. 777-780
Bioline Code: oc11132
Full paper language: English
Document type: Short Communication
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 106, No. 6, 2011, pp. 777-780

 en Validation of an immunochromatographic assay kit for the identification of the Mycobacterium tuberculosis check for this species in other resources complex
Toihir, Al-Habib; Rasolofo, Voahangy; Andrianarisoa, Samuel; Ranjalahy, Gabriel & Ramarokoto, Herimanana

Abstract

The performance of the immunochromatographic assay, SD BIOLINE TB Ag MPT64 RAPID®, was evaluated in Madagascar. Using mouse anti-MPT64 monoclonal antibodies for rapid discrimination between the Mycobacterium tuberculosis check for this species in other resources complex and nontuberculous mycobacteria, the kit was tested on mycobacteria and other pathogens using conventional methods as the gold standard. The results presented here indicate that this kit has excellent sensitivity (100%) and specificity (100%) compared to standard biochemical detection and can be easily used for the rapid identification of M. tuberculosis complex.

Keywords
Mycobacterium tuberculosis, Ag MPT64, Madagascar

 
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