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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 107, No. 7, 2012, pp. 953-954
Bioline Code: oc12201
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 107, No. 7, 2012, pp. 953-954

 en The prevalence of human cytomegalovirus DNA in gliomas of Brazilian patients
Fonseca, Renata Fragelli; Kawamura, Marcia Tie; Oliveira, José Antônio; Teixeira, Anselmo; Alves, Gilda & da Glória da Costa Carvalho, Maria

Abstract

Members of the Herpesviridae family have been implicated in a number of tumours in humans. At least 75% of the human population has had contact with cytomegalovirus (HCMV). In this work, we screened 75 Brazilian glioma biopsies for the presence of HCMV DNA sequences. HCMV DNA was detected in 36% (27/75) of the biopsies. It is possible that HCMV could be a co-factor in the evolution of brain tumours.

Keywords
brain tumour - glioma - cytomegalovirus - HCMV

 
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