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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 108, No. 1, 2013, pp. 23-29
Bioline Code: oc13004
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 108, No. 1, 2013, pp. 23-29

 en Clonal multidrug-resistant Corynebacterium striatum check for this species in other resources within a nosocomial environment, Rio de Janeiro, Brazil
Baio, Paulo Victor Pereira; Mota, Higor Franceschi; Freitas, Andréa D’avila; Gomes, Débora Leandro Rama; Ramos, Juliana Nunes; Sant’Anna, Lincoln Oliveira; Souza, Mônica Cristina; Camello, Thereza Cristina Ferreira; Junior, Raphael Hirata; Vieira, Verônica Viana & Mattos-Guaraldi, Ana Luíza

Abstract

Corynebacterium striatum check for this species in other resources is a potentially pathogenic microorganism with the ability to produce outbreaks of nosocomial infections. Here, we document a nosocomial outbreak caused by multidrug-resistant (MDR) C. striatum in Rio de Janeiro, Brazil. C. striatum identification was confirmed by 16S rRNA and rpoB gene sequencing. Fifteen C. striatum strains were isolated from adults (half of whom were 50 years of age and older). C. striatum was mostly isolated in pure culture from tracheal aspirates of patients undergoing endotracheal intubation procedures. The analysis by pulsed-field gel electrophoresis (PFGE) indicated the presence of four PFGE profiles, including two related clones of MDR strains (PFGE I and II). The data demonstrated the predominance of PFGE type I, comprising 11 MDR isolates that were mostly isolated from intensive care units and surgical wards. A potential causal link between death and MDR C. striatum (PFGE types I and II) infection was observed in five cases.

Keywords
Corynebacterium striatum - nosocomial outbreak - PFGE - multidrug-resistant clones

 
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