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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 108, No. 5, 2013, pp. 1-3
Bioline Code: oc13093
Full paper language: English
Document type: Short Communication
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 108, No. 5, 2013, pp. 1-3

 en Severity of tegumentary leishmaniasis is not exclusively associated with Leishmania RNA virus 1 infection in Brazil
Pereira, Luiza de Oliveira Ramos; Maretti-Mira, Ana Cláudia; Rodrigues, Káris Maria; Lima, Rosimar Baptista; de Oliveira-Neto, Manoel Paes; Cupolillo, Elisa; Pirmez, Claude & de Oliveira, Márcia Pereira

Abstract

Leishmania RNA virus (LRV) has been shown to be a symbiotic component of Leishmania parasites in South America. Nested retro-transcription polymerase chain reaction was employed to investigate LRV1 presence in leishmaniasis lesions from Brazil. In endemic areas of Rio de Janeiro (RJ), no LRV1 infection was observed even with mucosal involvement. LRV1 was only detected in Leishmania (V.) guyanensis check for this species in other resources cutaneous lesions from the northern region, which were obtained from patients presenting with disease reactivation after clinical cure of their primary lesions. Our results indicated that the severity of leishmaniasis in some areas of RJ, where Leishmania (V.) braziliensis check for this species in other resources is the primary etiological agent, was not associated with Leishmania LRV1 infection.

Keywords
Leishmania; LRV; tegumentary leishmaniasis; nested retro-transcription PCR

 
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