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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 108, No. 7, 2013, pp. 921-923
Bioline Code: oc13153
Full paper language: English
Document type: Short Communication
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 108, No. 7, 2013, pp. 921-923

 en Serologic survey of West Nile virus in horses from Central-West, Northeast and Southeast Brazil
Silva, Jaqueline Raymondi; de Medeiros, Larissa Campos; dos Reis, Vinícius Pinho; Chαvez, Juliana Helena; Munhoz, Thiago Demarchi; Borges, Gustavo Puia; Soares, Otavio Augusto Brioschi; de Campos, Carlos Henrique Coelho; Machado, Rosângela Zacarias; Baldani, Cristiane Divan; Silva, Maria Luana Cristiny Rodrigues; Faria, Joice Lara Maia; da Silva, Edson Elias & Figueiredo, Luiz Tadeu Moraes

Abstract

Since the emergence of West Nile virus (WNV) in North America in 1999, there have been several reports of WNV activity in Central and South American countries. To detect WNV in Brazil, we performed a serological survey of horses from different regions of Brazil using recombinant peptides from domain III of WNV. Positive samples were validated with the neutralisation test. Our results showed that of 79 ELISA-positive horses, nine expressed WNV-specific neutralising antibodies. Eight of the infected horses were from the state of Mato Grosso do Sul and one was from the state of Paraíba. Our results provide additional evidence for the emergence of WNV in Brazil and for its circulation in multiple regions of the country.

Keywords
West Nile virus; Flavivirus; Brazil

 
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