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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 108, No. 7, 2013, pp. 924-927
Bioline Code: oc13154
Full paper language: English
Document type: Short Communication
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 108, No. 7, 2013, pp. 924-927

 en Prevalence of plasmid-mediated quinolone resistance determinants among oxyiminocephalosporin-resistant Enterobacteriaceae in Argentina
Cruz, Giovanna Rincon; Radice, Marcela; Sennati, Samantha; Pallecchi, Lucia; Rossolini, Gian María; Gutkind, Gabriel & Di Conza, Jose Alejandro

Abstract

High quinolone resistance rates were observed among oxyiminocephalosporin-resistant enterobacteria. In the present study, we searched for the prevalence of plasmid-mediated quinolone resistance (PMQR) genes within the 55 oxyiminocephalosporin-resistant enterobacteria collected in a previous survey. The main PMQR determinants were aac(6’)-Ib-cr and qnrB, which had prevalence rates of 42.4% and 33.3%, respectively. The aac(6’)-Ib-cr gene was more frequently found in CTX-M-15-producing isolates, while qnrB was homogeneously distributed among all CTX-M producers.

Keywords
PMQR; ESBL-producing Enterobacteriaceae; fluoroquinolone

 
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