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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060 EISSN: 1678-8060
Vol. 109, No. 4, 2014, pp. 499-501
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Bioline Code: oc14078
Full paper language: English
Document type: Short Communication
Document available free of charge
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Memórias do Instituto Oswaldo Cruz, Vol. 109, No. 4, 2014, pp. 499-501
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Varicella zoster virus reactivation during or immediately following treatment of tegumentary leishmaniasis with antimony compounds
Barros, Andrea Barbieri; Rodrigues, Alex Miranda; Batista, Mariane Pereira; Junior, Sidney Munhoz; Hueb, Marcia & Fontes, Cor Jesus
Abstract
Antimony compounds are the cornerstone treatments for tegumentary leishmaniasis. The reactivation of herpes
virus is a side effect described in few reports. We conducted an observational study to describe the incidence of
herpes zoster reactivation during treatment with antimony compounds. The global incidence of herpes zoster is approximately
2.5 cases per 1,000 persons per month (or 30 cases per 1,000 persons per year). The estimated incidence
of herpes zoster in patients undergoing antimony therapy is higher than previously reported.
Keywords
leishmaniasis; herpes zoster; antimony therapy
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